Cancers of the testis are usually found in young adults and account for less than 1% of all malignancies in males. Cryptorchidism (undescended testicle) is a predisposing condition. Germ cell tumors of the testis are categorized into two main histologic types: seminomas and nonseminomas. The latter group is composed of either individual or combinations of histologic subtypes including embryonal carcinoma, teratoma, choriocarcinoma, and yolk sac tumor. The presence of serum markers, including alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and lactate dehydrogenase (LDH), is frequent in this disease. Staging is based on the determination of the extent of disease and assessment of serum tumor markers. Cancer of the testis is highly curable, even in cases with advanced disease.
Page Updated: 02/08/07, 01:43 PM