Bladder Cancer
Transitional cell carcinoma may occur at any site within the urinary collecting system from the renal calyx to the ureterovesical junction to the bladder and urethra. The tumors occur most commonly in adults and are rare before 40 years of age. There is a two- to three-fold increase in incidence in men compared with women, which increases further in smokers. The lesions are often multiple and are more common in patients with a prior history of transitional cell carcinoma of the bladder. Local staging depends upon the depth of invasion.
Bladder cancer can present as a low-grade papillary lesion, as an in situ lesion, which can occupy large areas of the mucosal surface, or as an infiltrative cancer that rapidly extends through the bladder wall. The papillary and in situ lesions may be associated with a malignant course, with sudden invasion of the bladder wall. Hematuria (blood in the urine) is the most common presenting sign.
Bladder Cancer Treatment Summaries
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Georgia Cancer Specialists, based in Atlanta, Georgia, is the largest private oncology and hematology practice in the Southeast with 41 physicians and 31 offices throughout the Atlanta and Macon areas.
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Page Updated: 02/08/07, 01:43 PM